Instrumentation
PRODUCTS
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Sulfide odor control within sanitary sewers has been practiced for over 50 years, yet only recently have substantive advances been made. Where once the choice of chemical treatment was either chlorine or iron salts, safer and more environmentally benign technologies based on nitrates, hydrogen peroxide, and/or magnesium hydroxide have gained acceptance. These new alternatives, however, can increase treatment costs substantially and present limitations in themselves. Therefore, it makes sense to explore new avenues for lessening the adverse impacts of the older, cheaper mainstays, particularly iron salts (ferrous/ferric chloride or sulfate) that provide other benefits to wastewater treatment operations.
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The CHOgro Expression System is an optimized platform for transient, high titer protein production in suspension CHO derived cells.
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BioBLU Single-Use Bioreactors combine the advantages of single-use technology with the trusted performance of stirred-tank design. Different variants are suitable for cell culture and microbial fermentation in R&D and clinical and commercial manufacturing. BioBLU Single-Use Bioreactors are compatible Eppendorf bioprocess controllers.
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When applied to plant influents, hydrogen peroxide destroys dissolved and/or total sulfide that otherwise scavenges Fe3+ added for CEPT and/or chemical phosphorus removal from wastewater. The foundational aspect of this PRI-TECH application (called PRI-CEPT) is that one lb of total sulfide theoretically consumes 3.5 lbs Fe3+ and thus represents an additional cost of $2 – 3 per lb influent sulfide.
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When AST came to the table on the design for our new fill-finish isolator, one of the first areas AST engineers wanted to address was the usability and accessibility of the isolator and corresponding operations. With our customers’ point of view in mind, we wanted to address specific points of friction routinely encountered by operators and closely examine whether those friction points were necessary.
Does an isolator need to be ergonomically unfriendly to clean?
Should simple mechanisms like isolator doors be challenging to engage? (As much as one can appreciate exercise, no one wants to do “arm day” in cleanroom coveralls).
Does routine maintenance have to be time-consuming and laborious?
Many of these factors are accepted as par for the course in aseptic fill-finish manufacturing. Our question was, why?
WHITE PAPERS AND CASE STUDIES
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Manufacturing Transfers: Delivering 140+ Precision Medical Devices Without Missing A Deadline
Go inside a successful manufacturing transfer of over 140 Class-III silicone medical devices and on-time delivery for a top-30 OEM through expert project management and rigorous validation processes.
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Mobile Gowning Cleanroom, Built To Meet ISO 7 Requirements
Uncover how Germfree designed and installed a mobile cGMP cleanroom on a 53′ tractor-trailer chassis to provide a flexible and efficient cleanroom solution tailored to the company’s needs.
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Accelerating Early Phase Oncology Study Development
Explore a close collaboration to co-develop a comprehensive, adaptive protocol designed to support key decisions across multiple trial phases for an innovative cancer therapy.
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Flexible Data Management For Growing Portfolio
Explore strategic enhancements to a small biopharma's biometrics capabilities involving the deployment of 20 specialized professionals, which effectively bolstered the client’s organizational capacity.
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CAR-T And Laminar Flow Glovebox Isolators
A request was made for a containment system that would protect operators during lentivirus transfer, as well as provide a controlled environment for IL-2 charging of media, bead addition, and blood bag spiking.
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Digital Transformation - The Power Of Your Data
Discover how you can circumvent numerous recirculations during the ultrafiltration process step, boost downstream bioprocess yield, and identify and resolve process inefficiencies.
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Leveraging Surface Plasmon Resonance For Characterizing Ternary Complexes
Uncover how Surface Plasmon Resonance (SPR) can be used to gain real-time, label-free insights into PROTAC binding kinetics and ternary complex formation.
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Rescuing A Global Program For NDA Success
Explore the collaboration that enabled FDA approval of a novel chronic-condition therapy, rescued a high-risk program, and demonstrated a unified “one-team” approach by reworking the sponsor's SAP.
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Multiple Fill Line Delivery Experience
Learn how a multinational pharmaceutical company successfully implemented a global strategy for insulin cartridge filling, achieving seamless regulatory approval with zero deviations.
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Controlling Biofouling In Governador José Richa Power Plant, Brazil
Read about an extensive study that was carried out to evaluate the ability of the HOD UV system to control biofouling in the Governador José Richa Power Plant.
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GxP Inventory Delivers Real-Time Visibility, Operational Efficiency
Modernize your clinical supply chain to streamline global trial operations, ensure regulatory compliance, and deliver investigational therapies to patients efficiently and reliably.
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How Easley Combined Utilities Cut Sludge Handling Costs By One-Third
Discover how a municipal wastewater treatment plant reduced its overall sludge management expenses by one-third and improved daily operational efficiency by implementing an advanced thickening system to streamline solids management and reduce hauling logistics.
NEWS
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Shell Expands Gulf Of America Leadership Position With Dover Development4/8/2025
Shell Offshore Inc. (Shell), a subsidiary of Shell plc, today announced the start of production at Dover, the second subsea tieback connecting new wells to the existing infrastructure of the Shell-operated Appomattox production hub in the Gulf of America.
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3-In-1 Orbital Thread Milling Cutters For New Thread Sizes1/14/2025
Following the successful introduction of the Thrill·tec TC645 Supreme orbital drill/thread mills for dimensions from M4 to M12 in 2023, Walter is now expanding its range to cover additional metric dimensions from M14 to M20 as well as their imperial equivalents.
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NX Filtration And Eau d'Azur Partner For Advanced Micropollutant Treatment In Nice8/25/2025
NX Filtration, a global leader in advanced hollow fiber membrane technology, is proud to announce its collaboration with Eau d’Azur, the public company responsible for drinking water and wastewater services for the Nice Côte d'Azur Metropole.
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The Persistence Of PFAS - IDTechEx Covers Growing PFAS Regulations4/24/2025
Per- and polyfluoroalkyl substances (PFAS) are a broad group of chemicals that includes both polymers and non-polymers used in many applications, from transport to consumer products.
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Motivosity Launches Lifestyle Spending Accounts To Help Companies Offer Flexible, Hassle-Free Employee Perks5/27/2025
Motivosity, the leading people-first employee recognition and rewards platform built for today’s workforce, is proud to announce the launch of its new Lifestyle Spending Accounts (LSAs) program.
ABOUT
Instrumentation
The science of measuring and controlling variables is termed instrumentation. As the name suggests, the process involves using a wide variety of instruments. These are classified as any device that can measure amounts that are physically quantifiable. These instruments do not have to be extremely complex in design. For example, the ruler is an instrument to measure distance, and a simple thermometer measures temperature.
Instruments specific to petrochemical processing include platinum Resistance Temperature Detectors (RTD’s), P/I Converters, many types of level meters, chromatographs, and continuous gas analyzers. These instruments are essential to the day to day instrumentation at petrochemical plants, as it is impossible to gauge to the necessary extent by estimation alone. Human error is inevitable, but an instrument can easily be calibrated or replaced.
Now that you understand the definition of and tools used in instrumentation, you should also understand the necessity of it. Temperature and pressure meters serve to ensure that the environment stays safe for both the chemicals being processed and the employees of the plant. Heat is a very well-documented activator in chemical reactions. If the temperature rises to unusual levels, this could spark an undesired chemical reaction that could prove catastrophic. The flow meter must measure how much oil is leaving the refinery, as it is a very volatile substance. Analytical instruments, such as the chromatograph, analyze the chemical make-up of the refined oil. This allows for the opportunity to make sure that the chemical make-up is correct, giving evidence that the process was correctly completed at all stages of refinement.