Instrumentation
PRODUCTS
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Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.
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Consider the benefits of an integrated operations and project management approach across all phases and regions.
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Access or Service hatches range in size, shape and function. Some service hatches are fitted with an enclosure shell for housing devices, with these type of hatches the primary barrier is maintained, regardless if the hatch door is open or closed.
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Providing around-the-clock support, enabled by at least two QPs per assignment, delivering full continuity, and reduced risk.
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This collaborative automated sample handler eliminates manual sample handling enabling testing of large sample sets and collection of statistically significant data, while freeing analyst’s time. The FMS Automation Module has a sample capacity of hundreds of vials and can complete headspace testing with a throughput as high as 300 samples per hour.
WHITE PAPERS AND CASE STUDIES
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Enhancing Municipal Water Storage With Submersible Mixers: A Case Study
Ice accumulation in water tanks poses serious challenges, compromising operations by trapping volumes of water and potentially costing tens of thousands of dollars in infrastructure damage. PAX Mixers are highly effective in preventing ice formation, even in extreme cold conditions. By optimizing water circulation, we can maintain consistent water temperatures within a tank.
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Automating The Process Of Filling Media Into Bottles
Learn how a vaccine manufacturer using a wide range of containers for media and buffer filling was able to increase efficiency by 70% with an automated closed-system solution.
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MilliporeSigma's 97-Day Implementation Success Story
Read how MilliporeSigma transformed validation processes with a digital validation system to achieve compliance in just 97 days, as well as learn key takeaways from their swift transition.
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Executing Concurrent Decentralized RCTs And RWE At Scale
See how a team of four managed data for 40 peer-reviewed studies and 200,000 participants.
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Flatiron Prospective Evidence Generation
Explore prospective evidence generation and pragmatic approaches that can help you address staffing challenges and the issue of complexity that is driving up the failure rate of clinical studies.
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Explore A High-Performing Basal Medium And Feed Pairing
A customer sought to replace a chemically defined CHO medium with a more efficient medium and feed pairing strategy in bioreactors.
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Navigate The Complexities Of CGTs With Regulatory And CMC Expertise
Explore how strategic regulatory and CMC expertise helped guide a biopharmaceutical company’s regulatory and development strategy for a cell and gene therapy product.
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Responsible Reclamation – City of Abilene, Texas
To combat drought, Abilene, Texas, implemented a reuse system utilizing O3 + BAC to remove trace organics. This solution met strict standards, ensured water resilience, and proved more cost-effective than AOP alternatives.
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AMERICAN SpiralWeld Pipe Delivers For City Of Phoenix Drought Pipeline Project
Phoenix’s Drought Pipeline Project, supported by AMERICAN SpiralWeld Pipe, secures clean water for North Phoenix, delivering up to 75 million gallons daily and earning top industry awards.
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Timely Lab Data To Inform Outreach To Healthcare Professionals
Learn how you can leverage a system that offers flexible data delivery formats and seamless integration into commercialization workflows while also ensuring HIPAA-compliant deidentified data for patient privacy.
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Eclipse Gear Pumps For Chemical Dosing: Santa Clara Regional Wastewater Facility
Read about the Santa Clara Regional Wastewater Facility, which is home to several Eclipse Pumps providing chemical dosing to municipal wastewater.
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Improving Clinical Research Efficiency And Access For Underserved Populations
Modernizing data workflows removes geographic barriers to clinical trials, ensuring rural patients access innovative care while reducing administrative burdens on dedicated research staff.
NEWS
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Meatable And TruMeat Collaborate To Accelerate Cost-Effective Cultivated Meat Production4/30/2025
Meatable, the leader in cultivated meat technology, and TruMeat, specializing in the contract manufacturing of cultivated meat at commercial scale, have formed a strategic collaboration to advance the global commercialization of cultivated meat.
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KBR Expands Support For Saudi's Energy Future1/22/2025
KBR announced today it has been awarded a contract to support sustainable production of energy resources in Saudi Arabia by contributing to the delivery of Saudi Aramco’s Master Expansion Program and increasing gas handling capacity at key regional locations.
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Puraffinity Signs First Commercial Agreement For Full-Scale Deployment Of Its PFAS Removal Technology6/2/2025
The agreement was signed with Envytech Solutions, the leading expert in mobile water treatment in the Nordic region and a member of the Sortera Group, which operates across the Nordics and the UK.
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GD Energy Products' Y-Shaped Drilling Module Now Rated For 10,000 PSI8/18/2025
GD Energy Products (GDEP), the leading total solutions provider for the frac, drilling and well servicing pumps market, has announced its patented Y-Shaped Drilling Module is now rated for operating pressures up to 10,000 psi.
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NX Filtration And Eau d'Azur Partner For Advanced Micropollutant Treatment In Nice8/25/2025
NX Filtration, a global leader in advanced hollow fiber membrane technology, is proud to announce its collaboration with Eau d’Azur, the public company responsible for drinking water and wastewater services for the Nice Côte d'Azur Metropole.
ABOUT
Instrumentation
The science of measuring and controlling variables is termed instrumentation. As the name suggests, the process involves using a wide variety of instruments. These are classified as any device that can measure amounts that are physically quantifiable. These instruments do not have to be extremely complex in design. For example, the ruler is an instrument to measure distance, and a simple thermometer measures temperature.
Instruments specific to petrochemical processing include platinum Resistance Temperature Detectors (RTD’s), P/I Converters, many types of level meters, chromatographs, and continuous gas analyzers. These instruments are essential to the day to day instrumentation at petrochemical plants, as it is impossible to gauge to the necessary extent by estimation alone. Human error is inevitable, but an instrument can easily be calibrated or replaced.
Now that you understand the definition of and tools used in instrumentation, you should also understand the necessity of it. Temperature and pressure meters serve to ensure that the environment stays safe for both the chemicals being processed and the employees of the plant. Heat is a very well-documented activator in chemical reactions. If the temperature rises to unusual levels, this could spark an undesired chemical reaction that could prove catastrophic. The flow meter must measure how much oil is leaving the refinery, as it is a very volatile substance. Analytical instruments, such as the chromatograph, analyze the chemical make-up of the refined oil. This allows for the opportunity to make sure that the chemical make-up is correct, giving evidence that the process was correctly completed at all stages of refinement.