Process Scale-Up And Scale-Out, Closure And Automation CDMO Services


CCRM has extensive experience in closing and automating various cell therapy processes.

  • Ability to automate process unit operations and demonstrate comparability to manual processing.  
  • Automation permits for improved process control and reproducibility required for meeting GMP manufacturing standards.
  • Optimization and translation of small scale cultures to closed, larger scale systems while improving viability, cell count, phenotype and intensifying the process. improving yield and reducing process time.  
  • Process closure enhances product safety by reducing contamination risk. 
  • Scale-up results in increased batch size reducing or eliminating the need for process scale-out reducing process foot print, time, and variability.

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