Catalysts
PRODUCTS
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We support you in the process of optimally implementing complex Manufacturing Execution Systems. In addition to the creation of Master Batch Records (MBRs) and Electronic Batch Recording (EBR), including classic data acquisition and preparation, as well as all other processes that have immediate effects on the manufacturing process.
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Antibody drug conjugates (ADCs) are the emerging class of anti-cancer therapeutic drugs. ADCs combine an antibody capable of recognizing cancer cells and cytotoxic small-molecule drugs via cleavable or non-cleavable linkers, thereby transforming the 3-unit combination into a targeted therapeutic drug for cancer treatment. In recent years, ADCs have rapidly developed and there are not only more than 14 approved drugs on the market but also many investigational drugs undergoing clinical trials. Furthermore, ADCs have shown potential for treating various diseases beyond cancer, such as Autoimmune disorders, Infectious diseases, Inflammatory conditions and so on.
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When AST came to the table on the design for our new fill-finish isolator, one of the first areas AST engineers wanted to address was the usability and accessibility of the isolator and corresponding operations. With our customers’ point of view in mind, we wanted to address specific points of friction routinely encountered by operators and closely examine whether those friction points were necessary.
Does an isolator need to be ergonomically unfriendly to clean?
Should simple mechanisms like isolator doors be challenging to engage? (As much as one can appreciate exercise, no one wants to do “arm day” in cleanroom coveralls).
Does routine maintenance have to be time-consuming and laborious?
Many of these factors are accepted as par for the course in aseptic fill-finish manufacturing. Our question was, why?
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Ideal for small batch sizes, many format changes, or a wide variety of packaging materials – the BE4 reliably meets all requirements. It enables a highly efficient process thanks to the two-lane operation with a very small footprint. Thanks to the 100% modular concept of the Blister Expert platform, the BE4 can be upgraded to a high-speed solution at any time.
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Clinical trials safety monitoring and reporting is vital to ensure participant safety, data integrity and regulatory compliance.
WHITE PAPERS AND CASE STUDIES
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Forge Boosts Efficiency And Compliance During External Collaboration
Streamlined collaboration and unified quality systems are helping CDMOs cut review times. Discover how connected workflows improve compliance and efficiency for faster delivery of life-changing treatments.
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Building A Scalable Oncology Engine In A Dynamic Market
Learn how a top-10 global pharmaceutical company partnered with Medable to rapidly scale the number of oncology trials it could concurrently conduct.
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The Role Of Hexapods In High-Precision Machining
A custom hexapod was introduced at ILA Berlin 2024, enhancing precision in aircraft construction. This 6-DOF system improves contour machining of CFRP components, reducing manufacturing times and costs.
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Phenotypic Characterization Of Bleomycin-Induced Pulmonary Fibrosis Mod
To gain deeper biological insight, lung injury in this model has been further characterized through cellular phenotyping, gene expression analysis, and cytokine profiling.
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CMO Validation As A Service
Learn about the highly successful commissioning and qualification of Wheeler's Oklahoma City CDMO facility with the overarching goal of ensuring all equipment was qualified for a Phase 3 clinical production campaign.
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Overcoming Participant Compliance Challenges In A Medical Device Study
Uncover how Catalyst Clinical Research enhanced participant compliance and streamlined scheduling for a TENS device study using the TrialKit platform, with crucial support from CDS.
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Recruiting High-Performing Sites To Beat Forecasted Trial Start Date
Explore a partnership that enabled Syneos Health to achieve its enrollment goals, increasing the likelihood of the study's success, and resulting in cost savings and maximized efficiency with minimal delays.
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How Green Chemistry Initiatives Reduced Cost While Increasing Yield
Green process redesign improved yield, reduced waste and solvent use, and cut manufacturing costs by 30% while enabling efficient, scalable production of an oncology compound.
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Large-Scale, 24/7 Mobile Quality Monitoring And Service Level Verification
Learn how CERN, the European Organization for Nuclear Research, created a reliable, cost-efficient, and fully compliant monitoring system for SLA verification with Android Probe and MNT solutions.
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Success In Times Of Crisis: A Journey From Concept To Market In 8 Months
Medbio ensures seamless tool transfers for medical device manufacturing by assessing tools, implementing improvements, and minimizing downtime to maintain quality, efficiency, and regulatory compliance.
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Choosing An R&D Data Management Platform For Novel Antibody Therapeutics
Uncover how this collaboration ensured the implementation of a robust electronic system that streamlined R&D operations, increased data integrity, and ultimately supported the development of novel antibody-based therapeutics.
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Lean Six Sigma Methodology Drives Cost Savings: 2 Success Stories
Unlock significant lab efficiency and financial gains. See how focused optimization of workflows and asset management led to substantial cost savings and reclaimed six-figure value in consumables.
NEWS
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New Technology Tracks Dairy Cows For Improved Health And Productivity1/30/2025
As dairy farmers dwindle every year, the demand for high-quality milk remains steadfast, driving a surge in dairy farming.
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SJW Infrastructure Improvement Progressing At Cambrian Tank Replacement Project5/29/2025
San Jose Water (“SJW” or “the Company”), a wholly owned subsidiary of H2O America, has made meaningful progress on its Cambrian Tank Replacement project, a major investment in the long-term reliability and seismic resilience of the Company’s water system.
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GD Energy Products' Y-Shaped Drilling Module Now Rated For 10,000 PSI8/18/2025
GD Energy Products (GDEP), the leading total solutions provider for the frac, drilling and well servicing pumps market, has announced its patented Y-Shaped Drilling Module is now rated for operating pressures up to 10,000 psi.
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Fine-Tuning Zinc Supplementation, Light Exposure To Boost Microgreens' Nutrition8/26/2025
Microgreens, which are young, edible plants that only take one to three weeks to harvest, are more than garnish at trendy restaurants — they could be the answer to global hunger, according to plant scientists at Penn State.
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ZEISS Introduces The New Smartzoom 100: The Future Of Digital Microscopy For Efficient Optical Inspections5/6/2025
ZEISS presents the new ZEISS Smartzoom 100, an innovative digital microscope for fast and efficient quality assurance.
ABOUT
Catalysts
Catalysts work by changing the structure of a molecule or by bonding to reactant molecules causing them to combine, react, and release a product or energy. For example, a catalyst is required in order for oxygen and hydrogen to bond, combine and produce water.
Catalysts increase the rate of chemical reactions. Unlike a reagent that gets consumed as apart of the chemical reaction, catalysts do not get consumed in the reaction. They can actually participate in multiple chemical transformations.Catalysts can be organic, synthetic or metal.
All processes need energy to take place. Processes require a very high level of energy in order to spark or start if a catalyst isn’t present. When a catalyst is present the amount of energy required to spark the reaction is lowered and that makes the reaction happen faster and more efficiently.
Catalytic effects vary depending on other substances present that are a part of the chemical reactions. There are certain substances that can inhibit the effectiveness of a catalyst like poisons, and other substances that promote or increase the effect of the catalyst. Inhibitors or negative catalysts are very important in medicine to treat mental illnesses, high blood pressure, cancer and many other diseases.
Catalysts are often used to help crack, or split, larger organic molecules like hydrocarbons into simpler molecules. It does this by breaking carbon-carbon bonds. The speed of the splitting process depends heavily on what specific catalyst is used and the temperature. Applications of this technology include oil and petrochemical industries.