Catalysts

WHITE PAPERS AND CASE STUDIES

• Preserving Pressure, Protecting Service: Upgrading Hydrant Infrastructure In Kent County

  When Kent County Water Authority faced the urgent replacement of a 94-year-old hydrant tied to a 1931 cast iron main, they were determined to maintain fire protection and avoid customer disruption.

• AMERICAN And Partners Install Boltless Restrained Underwater Pipeline System In Ashland, Wisconsin

  Beneath the waters of Chequamegon Bay on Lake Superior in Ashland, Wisconsin, about 4,500 feet of 24-inch AMERICAN Flex-Ring Ductile Iron Pipe and a submerged timber crib intake structure were installed to ensure the city’s residents have quality drinking water for the next 100 years. The Ashland Water Intake Project began May 1, 2025, and is now complete.

• Multiple Fill Line Delivery Experience

  Learn how a multinational pharmaceutical company successfully implemented a global strategy for insulin cartridge filling, achieving seamless regulatory approval with zero deviations.

• Predicting Food Effects In Oral Drug Delivery Using PBPK Modeling

  Learn how integrated PBPK and molecular dynamics modeling predicted an ~11% fed-state Cmax increase for fenofibrate, giving formulation teams earlier, mechanistic insight into food-dependent absorption.

• CAR-T And Laminar Flow Glovebox Isolators

  A request was made for a containment system that would protect operators during lentivirus transfer, as well as provide a controlled environment for IL-2 charging of media, bead addition, and blood bag spiking.

• Disinfection For Purified Water Loop For Kamada Pharmaceuticals, Israel

  An Atlantium HOD™ (Hydro-Optic Disinfection) UV system was installed at the outlet of a PW tank to serve as the primary disinfection barrier, with water circulating through the system at 6m³/hr before reaching the points of use.

• A Community-Focused Approach To Metabolic Disease Trials

  Learn how innovative strategies like free health exams, community engagement, and a comprehensive patient database helped this project achieve rapid enrollment with a high level of patient diversity.

• End-To-End Support To Advance Gene Therapies For Rare Retinal Diseases

  Learn how expert analytical testing and clinical support helped advance a promising gene therapy for rare retinal diseases from the lab to the clinic on an expedited timeline.

• Disinfection For Drinking Water Plant In Chennai, India

  The Chennai Metropolitan Water Supply and Sewerage Board (CMWSSB) encountered significant challenges in treating high algae loads at its drinking water plant, which processes 1.5 million liters of water daily. The primary issue arose from the organic load in lake water, which, when treated with conventional chlorine disinfectants, resulted in harmful disinfection byproducts (DBPs).

• Vassar WWTP Eliminates Rags To Protect Equipment, Biosolids Quality

  The Vassar wastewater treatment plant (WWTP) in Michigan confronted persistent challenges from non-dissolvable solids by adopting Duperon's Dual Auger System (DAS) to address these issues effectively.

• RTSM And Clinical Drug Dispensation

  A pharma company used Signant Health's RTSM solution in a Phase 2 schizophrenia trial to ensure drug availability, maintain study balance, prevent duplicate allocations, and manage returns and destruction of unused drugs.

• Navigate The Complexities Of CGTs With Regulatory And CMC Expertise

  Explore how strategic regulatory and CMC expertise helped guide a biopharmaceutical company’s regulatory and development strategy for a cell and gene therapy product.