Catalysts

WHITE PAPERS AND CASE STUDIES

• Fyfe - Drinking Water Reservoir Seismic Rehabilitation

  Upgrading reservoirs for seismic resilience requires high-strength, lightweight solutions. Fiber-reinforced polymer wraps provide essential structural reinforcement without adding dead weight, allowing for flexible, cost-effective installation that ensures long-term utility safety and continued community use of recreational spaces.

• Medable Beats Forecasted FPI Date While Raising eCOA Adherence In Japan

  A top-10 global pharmaceutical company aimed to address eCOA adherence and patient enrollment challenges faced by clinical trial sites and participants in Japan. See how they accomplished it and more with this case study.

• Helium Leak Detection On Glass Cartridge Containers

  Helium leak detection offers unmatched sensitivity for verifying glass cartridge seal integrity. Learn how this advanced method outperforms traditional tests and provides confidence in packaging.

• How Green Chemistry Initiatives Reduced Cost While Increasing Yield

  Green process redesign improved yield, reduced waste and solvent use, and cut manufacturing costs by 30% while enabling efficient, scalable production of an oncology compound.

• 12.5x Titer Boost Accelerates CAR-T Program To IND Filing

  Plasmid engineering and process development boosted viral titer 12.5×, eliminating manufacturing bottlenecks and enabling an on‑time regulatory submission for the cell therapy program.

• RWD's Significance In The Largest FDA-Funded IOL Study Of Pediatric Patients

  With FDA grant support, the American Academy of Ophthalmology and Verana Health conducted the largest real-world study to date on intraocular lens (IOL) use in pediatric cataract patients.

• Innovation Under Pressure: Navigating Clinical Trials Amid a Pandemic

  How do you complete a Phase 2b rheumatology study in three countries despite global lockdowns? Palleos cracked the code, achieving recruitment targets and regulatory approvals against all odds.

• Evansville Water & Sewer Utility: 4 Tactics For Managing & Organizing Vertical Assets

  EWSU, serving 65,000 customers, revamped its vertical asset tracking with POWER Engineers to enhance maintenance workflows. Here's how they optimized their processes.

• ProPharma Supports A Contract Manufacturer's Form 483 Response

  Learn how a small contract manufacturer navigated a complex FDA 483 Observation notice and implemented effective remediation strategies that addressed multiple system-wide concerns.

• Case Study: ThioBridge™ Conjugates

  Discover how Abzena’s ThioBridge™ technology is enabling the next generation of stable, scalable, and clinically advanced ADCs through site-specific conjugation.

• Overcoming Participant Compliance Challenges In A Medical Device Study

  Uncover how Catalyst Clinical Research enhanced participant compliance and streamlined scheduling for a TENS device study using the TrialKit platform, with crucial support from CDS.

• Lead Identification And Optimization For Computational Drug Discovery

  AI-generated Fab molecules promise speed, but can computational designs actually express and bind at scale? A high-throughput screening workflow offers a data-backed answer.